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Question:

Fill in the blanks with the most appropriate option that follows:

Clinical practitioners _____________ integrated mindfulness _____________ treatment of _____________ host of emotional and behavioural disorders, _____________ borderline personality disorder, major depression, chronic pain, or eating disorders. Number of such practitioners _____________ increased substantially.

Explanation:

The plural verb “have” makes for the most grammatically correct fit for the first blank from the options given. This eliminates options 3 and 5.
The verb in the last blank must attribute to the singular subject “number” and not “practitioners”. Thus, the correct verb to use is “has”. Eliminate options 1 and 2.
Integration of “mindfulness” therefore, has to be “for” the “treatment of a host of emotional and behavioral disorders.”.
Hence, the correct answer is option 4.

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