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Explanation:

Option 1 is incorrect as according to the paragraph, transgenic modification and genome editing are one and the same. Negate it. Option 2 is also incorrect as it mentions transgenic modification and genome editing to be two different processes. As per the second sentence of the paragraph, the editing of endogenous genes is exempted from regulations if the microbes are cultured in a contained environment. However, the penultimate paragraph states that exemption need not be made as there are unforeseen risks involved in the gene-editing. Thus option 3 is correct and can be retained. Though option 4 also states the same thing, it does not give any reason for its exception which is an important point in the paragraph. Thus it can be negated.
Hence, the correct answer is option 3.

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