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Explanation:

Options 1 and 4 are important issues as can be deciphered from the following extract, “The current debate on TRIPs in India - as indeed elsewhere echoes wider concerns about ‘privatisation’ of research and allowing a free field for MNCs in the sphere of biotechnology and agriculture.”
Option 3 is an important issue mentioned in the first paragraph. The paragraph mentions the relative roles of the public and private sectors as one of the important issues being raised in the current debate on IPRs.
Option 2 is not an important issue in the context of the passage. The first paragraph mentions “... the strategy and policies for building a more dynamic national agricultural research system ...” and not ‘the strategy and policies for building an IPR regime for Indian agriculture’ as being one of these issues.
Hence, the correct answer is option 2.

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