Discussion

Explanation:

As stated in the last paragraph, Dr. Serge Renaud found that the fat-derived cholesterol that builds up in the arteries and can eventually lead to heart trouble can be dispersed by the tannins in wine. Tannin is derived from the skins of grapes, and is therefore present in higher levels in red wines.
Option 4 supports this finding.
Option 1 does not explicitly indicate that film celebrities drink red wine. 
Option 2 weakens the statement by stating that red wine drinkers have higher levels of coronary heart incidence. So does option 3.
Option 3 states the opposite that red wine sales has a positive correlation with incidence of coronary heart disease.

Hence, the correct answer is option 4.

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